| Identification | Back Directory | [Name]
TD-0212 | [CAS]
1073549-10-6 | [Synonyms]
TD-0212
[1,1'-Biphenyl]-2-carboxylic acid, 4'-[[2-ethoxy-4-ethyl-5-[[[(2S)-2-mercapto-4-methyl-1-oxopentyl]amino]methyl]-1H-imidazol-1-yl]methyl]-3'-fluoro- | [Molecular Formula]
C28H34FN3O4S | [MDL Number]
MFCD31813766 | [MOL File]
1073549-10-6.mol | [Molecular Weight]
527.65 |
| Hazard Information | Back Directory | [Description]
TD-0212 is a potent, selective and orally active, dual AT1 antagonist/NEP inhibitor (ARNI) with At1 pKi-8.9 and NEP pIC50 = 9.2. TD-0212 produced blood pressure reductions similar to omapatrilat and combinations of AT1 receptor antagonists and NEP inhibitors. TD-0212 therefore provides the enhanced activity of dual AT1/NEP inhibition with a potentially lower risk of angioedema relative to dual ACE/NEP inhibition |
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| Company Name: |
DC Chemicals
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021-58447131 13564518121 |
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http://www.approvedhomemanagement.com/ShowSupplierProductsList927327/0.htm |
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