| Identification | Back Directory | [Name]
1-[(1,2-DIHYDRO-1-OXO-5-ISOQUINOLINYL)SULFONYL]HEXAHYDRO-1H-1,4-DIAZEPINE | [CAS]
105628-72-6 | [Synonyms]
Ha 1100
Fasudil Impurity L
1-[(1,2-DIHYDRO-1-OX
HA 1100 HYDROCHLORIDE
HA-1100;HA 1100;HA1100
HYDROXYFASUDIL;HA-1100;HA 1100;HA1100
5-((1,4-diazepan-1-yl)sulfonyl)isoquinolin-1-ol
5-((1,4-Diazepan-1-yl)sulfonyl)isoquinolin-1(2H)-one
5-(1,4-diazepane-1-sulfonyl)-1,2-dihydroisoquinolin-1-one
1(2H)-Isoquinolinone, 5-[(hexahydro-1H-1,4-diazepin-1-yl)sulfonyl]-
1-[(1,2-DIHYDRO-1-OXO-5-ISOQUINOLINYL)SULFONYL]HEXAHYDRO-1H-1,4-DIAZEPINE
Hexahydro-1-((1,2-dihydro-1-oxo-5-isoquinolinyl)sulfonyl)-1H-1,4-diazepine
1H-1,4-Diazepine, hexahydro-1-((1,2-dihydro-1-oxo-5-isoquinolinyl)sulfonyl)-
Fasudil impurity 12/5-(1,4-diazepan-1-ylsulfonyl)-2H-isoquinolin-1-one hydrochloride
1-[(1,2-Dihydro-1-oxo-5-isoquinolinyl)sulfonyl]hexahydro-1H-1,4-diazepinehydrochloride | [Molecular Formula]
C14H17N3O3S | [MDL Number]
MFCD01752417 | [MOL File]
105628-72-6.mol | [Molecular Weight]
307.37 |
| Hazard Information | Back Directory | [Biological Activity]
Cell-permeable active metabolite of Fasudil (HA 1077; Fasudil hydrochloride). Produces ATP-competitive and reversible inhibition of Rho-kinase and is ~ 100-fold selective over a range of other protein kinases. Inhibits neutrophil migration and produces potent vasodilatory effects in vivo . |
|
|