| Identification | Back Directory | [Name]
SPIROXATRINE | [CAS]
1054-88-2 | [Synonyms]
R 5188
SPIROXATRINE
Spiroxatrine (R 5188)
SPIROXATRINE (R 5188) SELECTIVE SEROTONI N 5
8-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
8-[(2,3-DIHYDRO-1,4-BENZODIOXIN-2-YL)METHYL]-1-PHENYL-1,3,8-TRIAZASPIRO[4,5]DECAN-4-ONE
1,3,8-Triazaspiro[4.5]decan-4-one, 8-[(2,3-dihydro-1,4-benzodioxin-2-yl)methyl]-1-phenyl-
8-((2,3-Dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
(+/-)-8-[(2,3-DIHYDRO-1,4-BENZODIOXIN-2-YL)METHYL]-1-PHENYL-1,3,8-TRIAZA-SPIRO[4,5]DECAN-4-ONE
R 5188, (±)-8-[(2,3-Dihydro-1,4-benzodioxin-2-yl)methyl]-1-phenyl-1,3,8-triaza-spiro[4,5]decan-4-one | [Molecular Formula]
C22H25N3O3 | [MDL Number]
MFCD00055134 | [MOL File]
1054-88-2.mol | [Molecular Weight]
379.45 |
| Chemical Properties | Back Directory | [Melting point ]
215.8-218.0 °C | [Boiling point ]
602.8±55.0 °C(Predicted) | [density ]
1.32±0.1 g/cm3(Predicted) | [storage temp. ]
Store at RT | [solubility ]
0.1 M HCl: moderately soluble | [form ]
powder | [pka]
15.03±0.20(Predicted) | [color ]
white |
| Hazard Information | Back Directory | [Uses]
Spiroxatrine (R 5188) is a SR-1A antagonist. | [Definition]
ChEBI: 8-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one is a member of imidazolidines. | [Biological Activity]
5-HT 1A antagonist. More active and selective than spiperone. Also a very potent α 2C adrenergic receptor antagonist. |
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| Company Name: |
BOC Sciences
|
| Tel: |
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| Website: |
https://www.bocsci.com |
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
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