| Identification | Back Directory | [Name]
GLU-GLY-VAL-ASN-ASP-ASN-GLU-GLU-GLY-PHE-PHE-SER-ALA-ARG | [CAS]
103213-49-6 | [Synonyms]
FGB
Fibrinogen beta chain
(GLU1)-FIBRINOPEPTIDE B
[GLU1]-FIBRINOPEPTIDE B HUMAN
[GLU1]-FIBRINOPEPTIDEB
Glu1]-Fibrinopeptide B human >=90% (HPLC)
Monoclonal Anti-FGB antibody produced in mouse
GLU-GLY-VAL-ASN-ASP-ASN-GLU-GLU-GLY-PHE-SER-ALA-ARG
GLU-GLY-VAL-ASN-ASP-ASN-GLU-GLU-GLY-PHE-PHE-SER-ALA-ARG
H-GLU-GLY-VAL-ASN-ASP-ASN-GLU-GLU-GLY-PHE-PHE-SER-ALA-ARG-OH
L-Arginine, L-α-glutamylglycyl-L-valyl-L-asparaginyl-L-α-aspartyl-L-asparaginyl-L-α-glutamyl-L-α-glutamylglycyl-L-phenylalanyl-L-phenylalanyl-L-seryl-L-alanyl- | [Molecular Formula]
C66H95N19O26 | [MDL Number]
MFCD00076440 | [MOL File]
103213-49-6.mol | [Molecular Weight]
1570.57 |
| Chemical Properties | Back Directory | [density ]
1.56±0.1 g/cm3(Predicted) | [storage temp. ]
-20°C | [form ]
Powder | [pka]
3.33±0.10(Predicted) | [color ]
White to off-white | [Water Solubility ]
Soluble in water at 1mg/ml |
| Hazard Information | Back Directory | [Uses]
[Glu^1] Fibrinopeptide B is used as a indicator of coagulation and fibrinolytic activity. And is useful for the tuning and calibration of electrospray ionization and MALDI mass spectrometers. | [General Description]
Fibrinopeptide B (FPB) is produced during the cleavage of fibrinogen, by thrombin, to fibrin monomer. It is cleaved off from the N-terminal of the fibrinogen β chain. This peptide is composed of 14 amino acids. | [Biochem/physiol Actions]
Fibrin formation is an essential part in wound healing and inflammation. Fibrinopeptide B (FPB) can also cause chemotactic migration of neutrophils, without the simultaneous release of lysosome enzymes. It is produced during the coagulation of fibrinogen, which is essential for physiological homeostasis. It is involved in various disorders such as thrombosis and disseminated intravascular coagulation. |
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