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ChemicalBook--->CAS DataBase List--->1031367-64-2

1031367-64-2

1031367-64-2 Structure

1031367-64-2 Structure
IdentificationBack Directory
[Name]

MC70
[CAS]

1031367-64-2
[Synonyms]

MC70
[Molecular Formula]

C24H25NO3
[MOL File]

1031367-64-2.mol
[Molecular Weight]

375.46
Chemical PropertiesBack Directory
[Boiling point ]

536.6±50.0 °C(Predicted)
[density ]

1.183±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMSO: soluble
[form ]

A crystalline solid
[pka]

9.80±0.26(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Description]

MC-70 is a potent P-gp inhibitor (EC50 = 0.69 μM). Multidrug resistance (MDR) is the major cause of the failure of cancer therapy since this phenomenon generates cancer cells that are unresponsive to chemotherapeutic agents. P-glycoprotein (P-gp) is a well-known membrane transporter expressed in a number of strategic biological barriers, where it exerts a protective effect of paramount importance.
[storage]

Store at -20°C
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