| Identification | Back Directory | [Name]
2-Benzylamino-2-methyl-1-propanol | [CAS]
10250-27-8 | [Synonyms]
2-Benzylamino-2-methyl-1-propanol
(Benzyl)(2-hydroxy-1,1-dimethylethyl)amine
2-Methyl-2-[(phenylmethyl)amino]-1-propanol
2-(benzylamino)-2-methyl-1-propanol(SALTDATA: HCl) | [EINECS(EC#)]
202-303-5 | [Molecular Formula]
C11H17NO | [MDL Number]
MFCD04500950 | [MOL File]
10250-27-8.mol | [Molecular Weight]
179.26 |
| Chemical Properties | Back Directory | [Appearance]
Yellow-Orange Solid | [Melting point ]
68-70℃ | [Boiling point ]
300.8±17.0 °C(Predicted) | [density ]
1.006±0.06 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Sealed in dry,2-8°C | [solubility ]
Chloroform, DMSO, Methanol | [form ]
Solid | [pka]
14.55±0.10(Predicted) | [color ]
Off-White | [InChI]
InChI=1S/C11H17NO/c1-11(2,9-13)12-8-10-6-4-3-5-7-10/h3-7,12-13H,8-9H2,1-2H3 | [InChIKey]
JIDHEIXSIHNMCG-UHFFFAOYSA-N | [SMILES]
C(O)C(C)(NCC1=CC=CC=C1)C | [CAS DataBase Reference]
10250-27-8 |
| Hazard Information | Back Directory | [Chemical Properties]
Yellow-Orange Solid | [Synthesis Reference(s)]
Tetrahedron, 44, p. 6801, 1988 DOI: 10.1016/S0040-4020(01)86206-2 | [Synthesis]
To a solution of 2-amino-2-methylpropan-1-ol (1 g, 11.22 mmol) and benzaldehyde (1.310 g, 12.34 mmol) in DCE (15 mL) at RT was added portionwise sodium triacetoxyborohydride (6.66 g, 31.4 mmol), and the mixture was stirred for 3 h. The mixture was diluted with EtOAc and washed with saturated aqueous NaHCO3. The organic layer was dried over MgSO4, filtered, and concentrated. The crude product 2-Benzylamino-2-methyl-1-propanol (1.247 g, 6.96 mmol, 62 % yield) was used without further purification. LCMS (m/z): 180.0 (M+H+). |
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