Identification | Back Directory | [Name]
GW791343 (HCl) | [CAS]
1019779-04-4 | [Synonyms]
CS-196 GW 791343 GW791343 (HCl) GW 791343 hydrochloride GW 791343 dihydrochloride GW791343 (dihydrochloride) 2-[(3,4-DIFLUOROPHENYL)AMINO]-N-[2-METHYL-5-(PIPERAZIN-1-YLMETHYL)PHENYL]ACETAMIDE 2-[(3,4-Difluorophenyl)amino]-N-[2-methyl-5-(1-piperazinylmethyl)phenyl]acetamide hydrochloride 2-[(3,4-Difluorophenyl)amino]-N-[2-methyl-5-(1-piperazinylmethyl)phenyl]-acetamidetrihydrochloride 2-((3,4-difluorophenyl)amino)-N-(2-methyl-5-(piperazin-1-ylmethyl)phenyl)acetamide dihydrochloride | [EINECS(EC#)]
200-258-5 | [Molecular Formula]
C20H24F2N4O | [MDL Number]
MFCD12828767 | [MOL File]
1019779-04-4.mol | [Molecular Weight]
374.428 |
Chemical Properties | Back Directory | [storage temp. ]
Desiccate at RT | [solubility ]
H2O : 100 mg/mL (223.54 mM; Need ultrasonic)DMSO : 20 mg/mL (44.71 mM; Need ultrasonic) | [form ]
Powder | [color ]
White to off-white |
Hazard Information | Back Directory | [Uses]
GW 791343 DTrihydrochloride is a P2X7 receptor antagonist that acts as an allosteric inhibitor, exhibiting negative allosteric effects at the human P2X7 receptor and positive allosteric effects at the
rat P2X7 receptor. P2X7 receptor is responsible for the presence of inflammatory cells, regulated by extracellular ATP. |
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NCE Biomedical Co.,Ltd.
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