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ChemicalBook--->CAS DataBase List--->101515-08-6

101515-08-6

101515-08-6 Structure

101515-08-6 Structure
IdentificationBack Directory
[Name]

-N7-DGTP
[CAS]

101515-08-6
[Synonyms]

-N7-DGTP
7-DEAZA-DGTP, LI
-N7-dGTP, 7-Deaza-dGTP
7-DEAZA-DGTP LITHIUM SALT
7-Deaza-2'-dGTP lithium salt
7-Deaza-dGTP,Sodium solution
2'-deoxy-7-deazaguanosine triphosphate
7-deaza-2'-deoxyguanosine 5'-*triphosphate lithiu
7-DEAZA-2'-DEOXYGUANOSINE 5'-*TRIPHOSPHA TE LITHIUM
7-DEAZA-2'-DEOXY-GUANOSINE-5'-TRIPHOSPHATE LITHIUM SALT
7-DEAZA-2'-DEOXYGUANOSINE-5'-TRIPHOSPHORIC ACID, LITHIUM
7-Deaza-2'-deoxyguanosine 5'-triphosphate lithium salt 10 mM in H2O
7-Deaza-2'-deoxyguanosine-5'-triphosphate sodium salt - 10mM aqueous solution
7-Deaza-2'-deoxyguanosine-5′-triphosphate lithium salt - 100mM aqueous solution
4H-Pyrrolo[2,3-d]pyrimidin-4-one, 2-amino-7-[2-deoxy-5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-erythro-pentofuranosyl]-3,7-dihydro-
[Molecular Formula]

C11H17N4O13P3
[MDL Number]

MFCD00171614
[MOL File]

101515-08-6.mol
[Molecular Weight]

506.19
Chemical PropertiesBack Directory
[density ]

2.48±0.1 g/cm3(Predicted)
[storage temp. ]

-20°C
[form ]

solution
[pka]

0.97±0.50(Predicted)
[color ]

colorless
Safety DataBack Directory
[Symbol(GHS) ]


GHS06
[Signal word ]

Danger
[Hazard statements ]

H301
[Precautionary statements ]

P264-P270-P301+P310-P321-P330-P405-P501
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

7-Deaza-dGTP is a substrate for most DNA polymerases, including Taq DNA polymerase.
7-Deaza-dGTP is used in the dideoxy-chain termination sequencing methods, in place of dGTP to overcome compression problems in gel electrophoresis when sequencing GC-rich stretches of DNA.
Partial substitution of 7-Deaza-dGTP for dGTP in PCRs can improve the product yield when the template is GC-rich (i.e., has extensive secondary structures).
[General Description]

7-Deaza-2′-deoxyguanosine 5′-triphosphate enhances polymerase chain reaction (PCR) product yield.
[Biochem/physiol Actions]

This dGTP analog pairs weakly with conventional bases to minimize DNA secondary structures, while being a good substrate for DNA ploymerases.
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