| Identification | Back Directory | [Name]
2-Piperidinecarboxamide, N-[4-(4-methoxyphenyl)-2-thiazolyl]-1-(phenylsulfonyl)- | [CAS]
1008671-38-2 | [Synonyms]
KCNQ1 activator-1
N-(4-(4-methoxyphenyl)thiazol-2-yl)-1-(phenylsulfonyl)piperidine-3-carboxamide
2-Piperidinecarboxamide, N-[4-(4-methoxyphenyl)-2-thiazolyl]-1-(phenylsulfonyl)- | [Molecular Formula]
C22H23N3O4S2 | [MOL File]
1008671-38-2.mol | [Molecular Weight]
457.57 |
| Chemical Properties | Back Directory | [density ]
1.364±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : 250 mg/mL (546.36 mM; Need ultrasonic) | [form ]
Solid | [pka]
8.37±0.70(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Biological Activity]
KCNQ1 activator-1 (compound 3) is a potent activator of KCNQ1 channel. KCNQ1 activator-1 has the potential for the research of long QT syndrome (LQTS)[1]. | [storage]
Store at -20°C | [References]
[1]. Mattmann ME, et al. Identification of (R)-N-(4-(4-methoxyphenyl)thiazol-2-yl)-1-tosylpiperidine-2-carboxamide, ML277, as a novel, potent and selective K(v)7.1 (KCNQ1) potassium channel activator. Bioorg Med Chem Lett. 2012;22(18):5936-5941. |
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DC Chemicals
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021-58447131 13564518121 |
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http://www.approvedhomemanagement.com/ShowSupplierProductsList927327/0.htm |
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nanjing
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13376082704 13376082704 |
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www.linye-e.com/ |
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