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ChemicalBook--->CAS DataBase List--->100665-40-5

100665-40-5

100665-40-5 Structure

100665-40-5 Structure
IdentificationBack Directory
[Name]

ganoderenic acid A
[CAS]

100665-40-5
[Synonyms]

ganoderenic acid A
(20E)-7β,15α-Dihydroxy-3,11,23-trioxolanosta-8,20(22)-diene-26-oic acid
(20E)-7β,15α-Dihydroxy-3,11,23-trioxo-5α-lanosta-8,20(22)-dien-26-oic acid
Lanosta-8,20(22)-dien-26-oicacid, 7,15-dihydroxy-3,11,23-trioxo-, (7b,15a,20E)-
Lanosta-8,20(22)-dien-26-oic acid, 7,15-dihydroxy-3,11,23-trioxo-, (7β,15α,20E)-
[Molecular Formula]

C30H42O7
[MDL Number]

MFCD07779161
[MOL File]

100665-40-5.mol
[Molecular Weight]

514.65
Chemical PropertiesBack Directory
[Boiling point ]

700.3±60.0 °C(Predicted)
[density ]

1.24±0.1 g/cm3(Predicted)
[solubility ]

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
[form ]

Powder
[pka]

4.65±0.23(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Description]

Ganoderenic acid A is a triterpenoid originally isolated from G. lucidum that has enzyme inhibitory activities. It is an inhibitor of β-glucuronidase (IC50 = 0.12 mg/ml in rat liver microsomes). Ganoderenic acid A (100 mg/kg) reduces increases in serum aspartate aminotransferase (AST), alanine aminotransferase (ALT), and lactate dehydrogenase (LDH) in a rat model of liver injury induced by carbon tetrachloride (CCl4). It also inhibits aldose reductase by 54.2% when used at a concentration of 100 μg/ml.
[Definition]

ChEBI:Ganoderenic acid A is a triterpenoid.
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