| Identification | Back Directory | [Name]
Z 060228 | [CAS]
1005459-82-4 | [Synonyms]
Z060228
Z-060228
Z 060228
5-Pyrimidinecarboxylic acid, 4-(2-chloro-4-fluorophenyl)-1,4-dihydro-6-methyl-2-(2,4,6-trifluorophenyl)-, ethyl ester, (4R)- | [Molecular Formula]
C20H15ClF4N2O2 | [MOL File]
1005459-82-4.mol | [Molecular Weight]
426.8 |
| Hazard Information | Back Directory | [Description]
Z060228 is an potent anti-HBV inhibitor. The HBV DNA replication in the supernatants of the HepG2.2.15 cells was effectively inhibited by Z060228. Z060228 exhibited effects on the self-assembly of Cp149. SEC data revealed that Z060228 altered the equilibrium (a state of stability) of Cp149 assembly. Z060228 could prevent Cp149 from self-assembling to the correct core particles. Z060228 was demonstrated to be a potential capsid targeting anti-HBV drug candidate. |
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