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ChemicalBook--->CAS DataBase List--->1005450-55-4

1005450-55-4

1005450-55-4 Structure

1005450-55-4 Structure
IdentificationBack Directory
[Name]

N-((R)-1-(naphthalen-1-yl)ethyl)-3-(3-(trifluoroMethyl)phenyl)propanaMide
[CAS]

1005450-55-4
[Synonyms]

Cinacalcet-11
-N-(1-(Naphthalen-1-yl)
Cinacalcet Impurity 117
Cinacalcet Impurity 31/Cinacalcet amide Impurity)
N-((R)-1-(naphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)pheny...
N-[1-(R)-(1-Naphthyl)ethyl]-3-[3-trifluoroMethylphenyl]propanaMide
(R)-N-(1-(phthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propamide
N-[1-(R)-(1-Naphthyl)ethyl]-3-[3-(trifluoromethyl)phenyl]-1-propanamide
N-《R)-I-(naphthalen-I-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propanamide
Benzenepropanamide, N-[(1R)-1-(1-naphthalenyl)ethyl]-3-(trifluoromethyl)-
N-((R)-1-(naphthalen-1-yl)ethyl)-3-(3-(trifluoroMethyl)phenyl)propanaMide
(R)-N-(1-(naphthalen-1-yl)ethyl)-3-(3-(trifluoroMethyl)phenyl)propanaMide
lN-((R)-1-(naphthalen-1-yl)ethyl)-3-(3-(trifluoroMethyl)phenyl)propanaMide
[Molecular Formula]

C22H20F3NO
[MDL Number]

MFCD18207041
[MOL File]

1005450-55-4.mol
[Molecular Weight]

371.4
Chemical PropertiesBack Directory
[Melting point ]

90-92℃ (cyclohexane )
[Boiling point ]

530.5±50.0 °C(Predicted)
[density ]

1.210±0.06 g/cm3(Predicted)
[storage temp. ]

Sealed in dry,Room Temperature
[solubility ]

Chloroform (Slightly), Methanol (Slightly)
[form ]

Solid
[pka]

15.18±0.46(Predicted)
[color ]

Off-White to Light Brown
[Stability:]

Hygroscopic
Hazard InformationBack Directory
[Uses]

N-((R)-1-(naphthalen-1-yl)ethyl)-3-(3-(trifluoroMethyl)phenyl)propanaMide(1005450-55-4) is a pharmaceutical intermediate ingredient used in the preparation of cinacalcet and its salts. Cinacalcet is used for the management and treatment of secondary hyperparathyroidism (in the dialysis population), primary hyperparathyroidism (where the patient may not be a candidate for surgical treatment), and for the treatment of end-stage renal disease or the prevention of calcification in dialysis patients.
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