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ChemicalBook--->CAS DataBase List--->1002342-83-7

1002342-83-7

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      1002342-83-7 Structure
      
                                
      
                                1002342-83-7 Structure
                            
      
                              		
                    
      
                
      
                
      IdentificationBack Directory
      [Name]

      Ald-PEG3-Azide
      [CAS]

      1002342-83-7
      [Synonyms]

      1002342-83-7
      Ald-PEG3-Azide
      CHO-PEG3-azide
      N3-PEG3-CH2CHO
      Ald-CH2-PEG3-N3
      ALD-CH2-PEG3-AZIDE
      [Molecular Formula]

      C8H15N3O4
      [MDL Number]

      MFCD24453193
      [MOL File]

      1002342-83-7.mol
      [Molecular Weight]

      217.23
      Chemical PropertiesBack Directory
      [solubility ]

      Soluble in Water, DMSO, DMF, DCM
      Hazard InformationBack Directory
      [Description]

      Ald-CH2-PEG3-azide is a click chemistry PEG linker. Aldehyde groups are likely to undergo nucleophile substitution, reduction and oxidation reactions. The azideN3 enable Click Chemistry reactions with alkynes, DBCO and BCN to form triazole groups. PEG3 spacer increases the water solubility of the compound.
      [Biological Activity]

      Ald-CH2-PEG3-azide is a cleavable 3-unit PEG-containing ADC linker that can be used to synthesize antibody drug conjugates (ADCs),it is a PROTAC linker belonging to the PEG class and can be used to synthesize PROTAC molecules.
      [in vitro]

       
       ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. 
       
         
      [target]

       
       
        Cleavable  
       
         
             		  
        PEGs  
       
         
       
      
                  		
            
            
                
                
      
                    
                        
      
                            
                                
                                
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                        Tags:1002342-83-7
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